nazli ayhan

Nazli Ayhan

Post-doctoral Researcher in Virology

Hello! While I was studying I was always interested in microbiology and especially virology. In 2014, I started my Ph.D. programme in Aix Marseille University, Faculty of Medicine, Department of Emergence of Viral Diseases with, Emerging Sandfly-borne Phleboviruses in Balkan Countries: Virus isolation, Characterization, Evolution and Seroepidemiology, subject. I am still working on vector borne viruses as a post-doctoral researcher.

Latest publications:

Seroprevalence of SARS-CoV-2 IgG antibodies, in Corsica (France).

Molecular screening of Anaplasmataceae in ticks collected from cattle in Corsica, France.

Education.

  • 2020-2021

    Post-Doctoral Unité de Virologie EA7310 Bioscope

    Unité de Virologie EA7310 Bioscope, Université de Corse Pasquale Paoli, Corsica, FRANCE

    Research Subject: Tick borne viruses and sero neutralisation assay automatisation.

  • 2017-2019

    Post-Doctoral Emergence of Viral Diseases

    Aix Marseille University, Marseille, FRANCE Faculty of Medicine, Department of Emergence of Viral Diseases

    Research Subject: Developing non-mammalian expression systems with using reverse genetic and re-coding systems in live attenuated Bunyaviruses.

  • 2014-2017

    PhD Emergence of Viral Diseases

    Aix Marseille University, Marseille, FRANCE Faculty of Medicine, Department of Emergence of Viral Diseases

    Thesis: Emerging Sandfly-borne Phleboviruses in Balkan Countries: Virus isolation, Characterization, Evolution and Seroepidemiology.

  • 2011-2013

    M.Sc Evolutionary Genetics

    Hacettepe University, Ankara, TURKEY Enstitute of Science, Department of Evolutionary Biology and Genetics
    CGPA: 3.91/4.00

    Thesis: The Effect of Food Restriction on the Genetic Variances of Development Time and Female Fecundity in Drosophila melanogaster Isolines.

  • 2008-2011

    B.S. Anthropology

    Hacettepe University, Ankara, TURKEY Faculty of Social Science, Department of Anthropology
    CGPA: 3.33/4.00

  • 2006-2011

    B.S. Biology

    Hacettepe University, Ankara, TURKEY Faculty of Science, Department of Biology
    CGPA: 3.19/4.00

Research Experience.

Microbiology Research

Internship Program in Gulhane Military Medical Academy Microbiology Department, Turkey

Medical Biology

Internship Program in Hacettepe University Medical Biology Department, Turkey

Evolutionary Biology

Research student in Hacettepe University, Biology Department, with Dr. Ergi Deniz Ozsoy and Dr. Banu Şebnem Önder, Turkey

Evolutionary Genetics

Intern Research Student in Groningen University Evolutionary Genetics Research Group, with Dr. Corneel Vermeulen, Netherlands

Virus isolation, Characterization, Evolution and Seroepidemiology

Aix Marseille University, Faculty of Medicine, with Dr. Remi Charrel, France

Arboviruses

Aix Marseille University, Faculty of Medicine, with Dr. Remi Charrel, France

Publications.

  • 28. Capai, L., Ayhan, N., Masse, S., Canarelli, J., Priet, S., Simeoni, M.H., Charrel, R.N., de Lamballerie, X. and Falchi, A. Seroprevalence of SARS-CoV-2 IgG antibodies, in Corsica (France), medRxiv, 2020.

  • 27. Cicculli, V., DeCarreaux, D., Ayhan, N., Casabianca, F., de Lamballerie, X., Charrel, R. and Falchi, A. Molecular screening of Anaplasmataceae in ticks collected from cattle in Corsica, France. Experimental and Applied Acarology, 81(4), pp.561-574. 2020.

  • 26. Muñoz, C., Ayhan, N., Ortuño, M., Ortiz, J., Gould, E.A., Maia, C., Berriatua, E., Charrel, R.N., 2020. Experimental Infection of Dogs with Toscana Virus and Sandfly Fever Sicilian Virus to Determine Their Potential as Possible Vertebrate Hosts. Microorganisms, 8(4), 596. 2020.

  • 25. Morini, S., Calzolari, M., Rossini, G., Pascarelli, N., Porcellini, A., Randi, V., Re, C.M, Albieri, A., Bonilauri, P., Bellini, B., Ayhan, N., Charrel, R., Varani, S. Detection of Specific Antibodies against Toscana Virus among Blood Donors in Northeastern Italy and Correlation with Sand Fly Abundance in 2014. Microorganisms, 8(2), 145.2020.

  • 24. Ayhan, N., Prudhomme, J., Laroche, L., Bañuls, A. L., Charrel, R. N. Broader Geographical Distribution of Toscana Virus in the Mediterranean Region Suggests the Existence of Larger Varieties of Sand Fly Vectors. Microorganisms, 8(1), 114. 2020

  • 23. Ayhan, N., and Charrel R. An update on Toscana virus distribution, genetics, medical and diagnostic aspects. Clinical Microbiology and Infection. 2020.

  • 22. Pereira, A., Ayhan, N., Cristóvão, J. M., Vilhena, H., Martins, Â., Cachola, P., Spitzova, T. Antibody Response to Toscana Virus and Sandfly Fever Sicilian Virus in Cats Naturally Exposed to Phlebotomine Sand Fly Bites in Portugal. Microorganisms, 7(9), 339. 2019

  • 21. Masse, S., Ayhan, N., Capai, L., Bosseur, F., de Lamballerie, X., Charrel, R. and Falchi, A. Circulation of Toscana Virus in a Sample Population of Corsica, France. Viruses, 11(9), 817. 2019

  • 20. Vaselek, S., Dvorak, V., Hlavackova, K., Ayhan, N., Halada, P., Oguz, G., Ivović, V., Ozbel, Y., Charrel, R.N., Alten, B. and Petrić, D. A survey of sand flies (Diptera, Phlebotominae) along recurrent transit routes in Serbia. Acta tropica, 105063. 2019

  • 19. Bino, S., Velo, E., Kadriaj, P., Kota, M., Moureau, G., Lamballerie, X., Bagramian, A., Charrel, R.N., Ayhan, N. Detection of a Novel Phlebovirus (Drin Virus) from Sand Flies in Albania. Viruses, 11, 469. 2019

  • 18. Jancarova, M., Bichaud, L., Hlavacova, J., Priet, S., Ayhan, N., Spitzova, T., Volf, P. and Charrel, R.N. Experimental Infection of Sand Flies by Massilia Virus and Viral Transmission by Co-Feeding on Sugar Meal. Viruses, 11(4), 332. 2019

  • 17. Ayhan, N. and Charrel, R.N. Emergent Sand Fly–Borne Phleboviruses in the Balkan Region. Emerging Infectious Diseases, 24(12), 2324. 2018

  • 16. Pudar, D., Petrić, D., Allène, X., Alten, B., Ayhan, N., Cvetkovikj, A., Garros, C., Goletić, T., Gunay, F., Hlavackova, K. and Ćupina, A.I. An update of the Culicoides (Diptera: Ceratopogonidae) checklist for the Balkans. Parasites & Vectors, 11(1), 462. 2018

  • 15. Alkan, C., Moin Vaziri, V., Ayhan, N., Badakhshan, M., Bichaud, L., Rahbarian, N., Javadian E. A., Alten, B., de Lamballerie, X., Charrel, R. N. Isolation and sequencing of Dashli virus, a novel Sicilian-like virus in sandflies from Iran; genetic and phylogenetic evidence for the creation of one novel species within the Phlebovirus genus in the Bunyaviridae family. PLoS Neglected Tropical Diseases, 11(12). 2017

  • 14. Ayhan, N., Alten, B., Ivovic, V., Martinkovic, F., E Kasap, O., Ozbel, Y., de Lamballerie, X., Charrel, R.N. Co-circulation of two lineages of Toscana virus in Croatia. Frontiers in Public Health, 5, 336. 2017

  • 13. Vaselek, S., Ayhan, N., Oguz, G., Kasap, O. E., Savić, S., Di Muccio, T.,Gradoni, L., Ozbel Y., Alten, B., Petrić, D. Sand fly and Leishmania spp. survey in Vojvodina (Serbia): first detection of Leishmania infantum DNA in sand flies and the first record of Phlebotomus (Transphlebotomus) mascittii Grassi, 1908. Parasites & Vectors, 10(1), 444. 2017

  • 12. Ayhan, N., Charrel, R.N. Of Phlebotomines (Sandflies) and Viruses: A Comprehensive Perspective On A Complex Situation. Current Opinion in Insect Science, 22, 117-124. 2017

  • 11. Ayhan, N., Sherifi, K., Taraku, A., Bërxholi, K., Charrel, R.N. High Rates of Neutralizing Antibodies to Toscana and Sandfly Fever Sicilian Viruses in Livestock, Kosovo. Emerging infectious diseases, 23(6), 989. 2017

  • 10. Pierro, A., Ficarelli, S., Ayhan, N., Morini, S., Raumer, L., Bartoletti, M., Mastroianni, A., Prati, F., Schivazappa S., Cenni, P., Vocale, C., Rossini, G., Gaibani, P., Sambri, V., Landini M.P. Characterization of antibody response in neuroinvasive infection caused by Toscana virus. Clinical Microbiology and Infection, 23(11), 868-873. 2017

  • 9. Ayhan, N., Alten, B., Ivovic, V., Dvorak, V., Martinkovic, F., Omeragic, J., Stefanovska, J., Petric, D., Vaselek, S., Baymak, D., Kasap, O.E., Volf, P., Charrel, N.R. Direct evidence for an expanded circulation area of the recently identified Balkan virus (Sandfly fever Naples virus species) in several countries of the Balkan archipelago. Parasites & Vectors. 10(1), 402. 2017

  • 8. Ayhan, N., Gueler, P., Onder, B.S. Lipocalin gene expression is varied in developmental stages by larval nutritional stress in Drosophila. Turkish Journal of Biology. 41(1), 178-186. 2017

  • 7. Huemer, H., Prudhomme, J., Amaro, F., Baklouti A., Walder, G., Alten, B., Moutailler, S., Ergunay, K., Charrel, R.N., Ayhan, N. Practical guidelines for studies on sandfly-borne phleboviruses: part II: important points to consider for field work and subsequent virological screening. Vector Borne Zoonotic Diseases. 17(1):81-90. 2016

  • 6. Ayhan, N., Baklouti A., Prudhomme, J., Walder, G., Amaro, F., Alten, B., Moutailler, S., Ergunay, K., Charrel, R.N., Huemer H. Practical guidelines for studies on sandfly-borne phleboviruses: part I: important points to consider ante field work. Vector Borne Zoonotic Diseases. 17(1): 73-80. 2016

  • 5. Ayhan, N., Velo, E., de Lamballerie, X., Kota, M., Kadriaj, P., Ozbel, Y., Charrel, R.N., Bino, S. Detection of Leishmania infantum and a novel phlebovirus (Balkan virus) from sand flies in Albania. Vector Borne Zoonotic Diseases. 2016

  • 4. Alwassouf, S., Maia, C., Ayhan, N., Coimbra, M., Cristovao, J.M., Richet, H., Charrel, R.N. Neutralisation-based seroprevalence of Toscana virus and Sandfly fever Sicilian virus in dogs and cats from Portugal. Journal of General Virology. 97(11). 2016

  • 3. Ergunay, K., Ayhan, N., Charrel, R.N. Novel and emergent sandfly‐borne phleboviruses in Asia Minor: a systematic review. Reviews in Medical Virology. 2016

  • 2. Ayhan, N., Guler, P., Onder. B.S. The Effect of Dietary Stress on the Genetic Variances of Life History Traits in Drosophila melanogaster. Journal of Thermal Biology. 2016

  • 1. Guler, P., Ayhan, N., Koşukcu, C. and Onder, B.S. The effects of larval diet restriction on developmental time, pre-adult survival and wing length in Drosophila melanogaster. Turkish Journal of Zoology. 39(3): 395-403, 2015

Books.

  • Ayhan, N. and Charrel, R.N. Sandfly-Borne Viruses of Demonstrated / Relevant Medical Importance. In Vectors and Vector Borne Zoonotic Diseases. IntechOpen. 2018

Presentations.

Scientific Activities.

Sand fly collection field work

VectorNet, 22 June - 04 July 2014, 1 July – 2 September 2015

Bosnia-Herzegovina, Montenegro, Croatia, Serbia, Bulgaria, Macedonia and Kosovo.

Mathematical Evolution Work-Shop

Nesin Mathematics School, 9-15 September 2013

Şirince, Izmir/ Turkey

Darwin Scholarship Program

Field Studies Council, 20-30 August 2013

Shrewsbury, London / United Kingdom

Fifth Nature Education in Kaçkar Mountain National Park

The Scientific and Technological Research Council of Turkey, 16-25 August 2010

Samsun / Turkey

Cernek Bird Ringing Station

Ondokuz Mayıs University, 04-11 September 2009

Artvin / Turkey

Ninth Bird Watching School

Gazi University, 07-08 March 2009

Ankara / Turkey

Underwater Science Camp

The Scientific and Technological Research Council of Turkey, 05-20 July 2008

Antalya/ Turkey

Collaborations.

  • 2019

    Tehmina Bharucha

    Doctor from Institute of Glycobiology, Department of Biochemistry, South Parks Road, Oxford / United Kingdom
    23.09.2019 – 31.10.2019

  • 2019

    Carla Maia

    Rearcher from Global Health and Tropical Medicine (GHMT), Universidade Nova de Lisboa, Lisboa / Portugal
    11.02.2019 – 01.03.2019

  • 2018

    Cristina Cazan

    PhD student from University of Cluj - Napoca / Romania
    16.01.2018 – 15.03.2018

  • 2017

    Clara Munoz Hernandez

    PhD student from University of Murcia / Spain
    01.03.2017 – 04.05.2017

  • 2016

    Slavica Vaselek

    PhD student from University of Novi-Sad / Serbia
    22.09.2016 – 09.11.2016

Trained Students.

  • 2018

    Ani Bagramian

    internship student from University of Claude Bernard Lyon 1 / France
    03.01.2018 – 01.06.2018

  • 2017

    Kahina Bennai

    internship student from M’hamed Bougara Boumerdes University / Algeria
    03.06.2017 – 15.07.2017

  • 2017

    Kivanc Sevim

    internship student from Hacettepe University / Turkey
    27.06.2017 – 21.09.2017

Contact.

nazliayhann@gmail.com
  • Aix Marseille University Faculty of Medicine,
  • Department of Emergence of Viral Diseases, UMR190
  • Marseille, FRANCE
  • Université de Corse Pasquale Paoli,
  • Unité de Virologie EA7310 Bioscope
  • Corsica, FRANCE